Gaining body weight despite exercising and eating less? An imbalance of insulin in the body can be attributed to this.
This was revealed in a medical study in Switzerland.
Well, it is already known that excess body weight has negative effects on blood sugar levels and increases the risk of diabetes.
But a study by the University of Basel found that this process can also be reversed, i.e. lack of insulin in the body can also lead to obesity.
Research has shown that if insulin production is affected, as in the early stages of type 2 diabetes, weight gain may also increase.
The study focused on PC1/3, an important physiological enzyme that is essential for many hormones.
If this enzyme does not work properly, several problems such as excessive appetite and obesity may occur.
During the research, experiments conducted on mice showed that when PC1/3 was turned off in the pancreatic cells, these animals began to overeat, causing them to quickly become obese and diabetic.
The researchers said the findings are very interesting because PC1/3 levels are reduced in the pancreas of patients with high blood sugar.
He said that this indicates that a decrease in insulin intake not only increases the risk of diabetes, but can also increase body weight.
He said that an adequate amount of this enzyme in the body helps in maintaining a healthy body weight.
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